Profile of <em>b</em>NRAMP1 Gene Sequence as the Candidate Gene for Pathogenic Bacterial Resistance Trait in Cattle

Widya Pintaka Bayu Putra Bayu

doi:https://doi.org/10.29329/ijiaar.2019.217.17

Review article | Open Access
International Journal of Innovative Approaches in Agricultural Research 2019, Vol. 3(4) 706-712

Profile of bNRAMP1 Gene Sequence as the Candidate Gene for Pathogenic Bacterial Resistance Trait in Cattle

Widya Pintaka Bayu Putra Bayu

pp. 706 - 712 | DOI: https://doi.org/10.29329/ijiaar.2019.217.17

Published online: December 10, 2019 | Number of Views: 98 | Number of Download: 631

Download PDF

Abstract

Bovine Natural Resistance Associated Macrophage Protein 1 (bNRAMP1) gene is one of the candidate gene that widely used to control the infectious disease in dairy and beef cattle. In mouse, the bNRAMP1 gene is important to confer resistance or suspectibility to Mycobacterium bovis, Salmonella typhimurium and Leishmania donovani. This article was carried out to explain the profile of bNRAMP gene such as genes structure, number of Single Nucleotide Polymorphisms (SNPs) and its relationship to pathogenic bacterial diseases evidence such as bovine Tuberculosis, mastitis and Brucellosis. The mutations (SNPs) in bNRAMP1 gene were occured in intron, exon and 3"UTR regions. Previous studies reported that some SNPs in bNRAMP1 gene affected to many pathogenic bacterial disease incidences in cattle. Hence, the bNRAMP1 gene can be used as the genetic marker for pathogenic bacterial resistance trait

Keywords: bNRAMP1 gene, Genes structure, SNP, diseases resistance

How to Cite this Article

APA 6th edition
Bayu, W.P.B.P. (2019). Profile of bNRAMP1 Gene Sequence as the Candidate Gene for Pathogenic Bacterial Resistance Trait in Cattle . International Journal of Innovative Approaches in Agricultural Research, 3(4), 706-712. doi: 10.29329/ijiaar.2019.217.17

Harvard
Bayu, W. (2019). Profile of bNRAMP1 Gene Sequence as the Candidate Gene for Pathogenic Bacterial Resistance Trait in Cattle . International Journal of Innovative Approaches in Agricultural Research, 3(4), pp. 706-712.

Chicago 16th edition
Bayu, Widya Pintaka Bayu Putra (2019). "Profile of bNRAMP1 Gene Sequence as the Candidate Gene for Pathogenic Bacterial Resistance Trait in Cattle ". International Journal of Innovative Approaches in Agricultural Research 3 (4):706-712. doi:10.29329/ijiaar.2019.217.17.

References

Ables, G. P., M. Nishibori, M. Kanemaki and T. Watanabe. (2002). Sequence analysis of the NRAMP1 genes from different bovine and buffaloe breeds. J. Vet. Med. Sci., 64 (11), 1081-1083. [Google Scholar]
Allen, A. R., G. Minozzi, E. J. Glass, R. A. Skuce, S. W. J. McDowell, J. A. Woolliams and S. C. Bishop (2010). Bovine tuberculosis: the genetic basis of host susceptibility. Proc. Royal Soc., 277, 2737-2745. [Google Scholar]
Baqir, M., S Bhusan, A. Kumar, A. Sonawane, R. Singh, A. Chauhan, R. Yadav, O. Prakash, R. Renjith, A. Baladhare and D. Sharma (2016). Association of polymorphisms in SLC11A1 gene with bovine tuberculosis trait among Indian cattle. J. Appl. Anim. Res., 44 (1), 380-383. [Google Scholar]
Cellier, M., G. Prive, A. Belouchi, T. Kwan, V Rodrigues, W. Chia and P. Gros (1995). Nramp defines a family of membrane proteins. [Proceedings of the National Academy of Sciences of the United States of America], 10089-10093 [Google Scholar]
Cheng, Y., C. S. Huang and H. J. Tsai (2015). Relationships of bovine SLC11A1 (formerly NRAMP1) polymorphisms to the risk of Bovine Tuberculosis in Holstein cattle. J. Vet. Sci. Tech., 6 (5), 1-6. [Google Scholar]
Cosivi, O., J. M. Grange, C. J. Daborn, M. C. Raviglione, T. Fujikura, D. Cousins, R. A. Robinson, H. F. Huchzermeyer, I. de Kantor and F. X. Meslin (1998). Zoonotic tuberculosis due to Mycobacterium bovis in developing countries. Emerg. Infect. Dis., 4 (1), 59-70. [Google Scholar]
Coussens, P. M., M. J. Coussens, B. C. Tooker and W. Nobis (2004). Structure of the bovine natural resistance associated protein (NRAMP1) gene and identification of a novel polymorphism. DNA Sequence, 15 (1), 15-25. [Google Scholar]
Estrada-Chavez, C., A. L. Pereira-Suarez, M. A. Meraz, C. Arriaga, A. Garcia-Carranca, C. Sanchez-Rodriguez and R. Mancilla. 2001. High-level expression of NRAMP1 in peripheral blood cells Tuberculous Granulomas from Mycobacterium bovis - infected bovines. Infect. Immun., 11, 7165-7168. [Google Scholar]
Feng, J., Y. Li, M. Hashad, E. Schurr, P. Gros, L. G. Adams and J. W. Templeton (1996). Bovine natural resistance associated macrophage protein 1 (Nramp1) gene. Genom. Res., 6, 956-964. [Google Scholar]
Gonzales, J. P., O. A. Saldarriaga, A. Lopez-Herrera, N. R. Bermudez, W. Zabata, J. E. Ossa, M. T. Rugeles and G. Bedoya (2006). Polymorphism in 1908STR1934 locus of the 3'UTR of the Nramp1 bovine gene in eight cattle breeds. Rev. Col. Cienc. Pec., 19 (1), 11-17. [Google Scholar]
Horin, P., I. Rychlik, J. W. Templeton and L. G. Adams. 1999. A complex pattern of microsatellite polymorphism within the bovine NRAMP1 gene. Europ. J. of Immunogenet., 26, 311-313. [Google Scholar]
Joo, Y. S., J. S. Moon, L. K. Fox, G. H. Suh, N. H. Kwon, S. H. Kim and Y. H. Park (2003). Comparison of natural resistance - associated macrophage protein (NRAMP)1 expression between cows with high and low milk somatic cells count. Asian-Australas J. Anim. Sci., 16 (12), 1830 - 1836. [Google Scholar]
Kadarmideen, H. N., A. A. Ali, P. C. Thomson, B. Muller and J. Zinsstag (2011). Polymorphisms of the SLC11A1 gene and resistance to bovine tuberculosis in African Zebu cattle. Anim. Genet., 42 (6), 656-658. [Google Scholar]
Kuhn, D. E., B. D. Baker, W. P. Lafuse and B. S. Zwilling (1999). Differential iron transport into phagosomes isolated from the RAW264.7 macrophage cell lines transfected with Nramp1Gly169 or Nramp1Asp169. J. Leukoc. Biol., 66, 113-119. [Google Scholar]
Kumar, N., A. Mitra, I. Ganguly, R. Singh, S. M. Deb, S. K. Srivastava and A. Sharma (2005). Lack of association of brucellosis resistance with (GT)13 microsatellite allele at 3'UTR of NRAMP1 gene in Indian zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle. Vet. Microbiol., 111: 139-143. [Google Scholar]
Kumar, N., I. Ganguly, R. Singh, S. M. Deb, S. Kumar, A. Sharma and A. Mitra (2011). DNA polymorphism in SLC11A1 gene and its association with brucellosis resistance in Indian Zebu (Bos indicus) and crossbred (Bos indicus × Bos taurus) cattle. Asian-Australas J. Anim. Scie., 24 (7): 898-904. [Google Scholar]
Liu, K., B. Zhang, Z. Teng, Y. Wang, G. Dong, C. Xu, B Qin, C. Song, J. Chai, Y. Li, X. Shi, X. Shu and Y. Zhang (2016). Association between SLC11A1 (NRAMP1) polymorphisms and susceptibility to tuberculosis in Chinese Holstein cattle. Tuberculosis, 30, 1-7. [Google Scholar]
Martinez, R., S. Dunner, G. Barrera, J. Canon. (2008). Novel variants within the coding regions of the Slc11a1 gene identified in Bos taurus and Bos indicus breeds. J. Anim. Breed. Genet., 125: 57-62. [Google Scholar]
Paixao, T. A., R. Martinez and R. L. Santos (2012). Polymorphisms of the coding region of Slc11a1 (Nramp1) gene associated to natural resistance against bovine brucellosis. Arq. Bras. Med. Vet. Zootec., 64 (4), 1081-1084. [Google Scholar]
Ranjan, R., C. D. Bhong, K. V. Chavan, S. N. S. Parmar and C. G. Joshi (2011). DNA polymorphism of 3'UTR of Nramp1 gene in Malvi breed of cattle. J. Adv. Vet. Res., 1, 105-108. [Google Scholar]
Schutta, C. J. (2006). Bovine SLC11A1: Genomic Sequence Variation and Functional Analysis in Cattle Naturally Resistant and Susceptible to Bovine Brucellosis. Ph.D. Dissertation, Texas A & M University, Texas, USA, p. 80. [Google Scholar]
Swilling, B. S., D. E. Kuhn, L. Wikoff, D. Brown and W. Lafuse (1999). Role of iron in Nramp1- mediated inhibition of mycobacterial growth. Infect. Immun., 67, 1386-1392. [Google Scholar]
Vidal, S. M., D. Malo, K. Vogan, E. Skamene and P. Gros (1993). Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg. Cell, 73 (3), 469-485. [Google Scholar]

Volume 3 Issue 4

December 2019

All Articles